Gather initial thoughts and broad opinions about the book.

1. How do you feel about the dynamic between Korede and Ayoola? Do you think Ayoola asks too much of Korede? Do you think Korede is too passive and fails to resist Ayoola’s behavior?

2. Were you satisfied by the novel’s ending? Do you feel that the narrative prepared you for Korede’s decision to protect her sister? Elaborate on the plot beats that made you feel this way.

3. In Frieda McFadden’s The Locked Door, the protagonist is related to a serial killer who occupies an antagonistic role in the narrative. Discuss how My Sister, the Serial Killer subverted your expectations about the portrayal of serial killers and psychopathy.

Encourage readers to connect the book’s themes and characters with their personal experiences.

1. Do you personally believe that physical appearance should affect the way people treat one another? How do you reconcile your beliefs with the way people react to Korede’s and Ayoola’s physical appearances?

2. The novel suggests that Ayoola may have inherited behavioral traits from her narcissistic father. Where do you stand in the debate between nature and nurture? Do you think Ayoola’s penchant for murder stems from a fundamental aspect of her character? Or do you feel the way she was raised influenced her behavior?